The hormonal components of Nordette 28 inhibit ovulation by suppressing gonadotropin release. Secondary mechanisms which may contribute to the effectiveness of Nordette 28 as a contraceptive include changes in the cervical mucus (which increase the difficulty of sperm penetration) and changes in the endometrium (which reduce the likelihood of implantation).

Oral levonorgestrel with ethinyl estradiol is a combination of progestin and estrogen contraceptive agent. It is used for long-term birth control and regulation of monthly menstrual cycles. Levonorgestrel is the progestin component while ethinyl estradiol is the estrogen component.

FDA Approved Uses for Nordette

Used to prevent pregnancy.

Used to regulate the menstrual cycle.

Contraindications

Any of the following may be reason to choose a different drug. Inform your doctor before starting therapy.

Allergic to any component of this combination or any estrogen or progestin
Breast cancer
Endometrial cancer
Estrogen-dependent cancer
Thrombophlebitis or thromboembolic disorders
Known or suspected pregnancy
Coronary artery disease
Unexplained uterine bleeding
Severe liver disease

Dosage and Administration

Dosages may require modification to adjust for individual sensitivities and associated medical conditions.

Adults Under 60

Package of 21: Start on Day 1 of the menstrual cycle or on the first Sunday after the menstrual cycle begins. Take one tablet by mouth everyday for a total of 21 days, then stop for 7 days. Repeat the 28 day cycle.

Package of 28: Start on Day 1 of the menstrual cycle or on the first Sunday after the menstrual cycle begins. Take one tablet by mouth everyday for a total of 28 days as directed on the package (the last 7 tablets have no hormones in them). Repeat the 28 day cycle.

Take at the same time each day. When starting the first cycle, use a back-up birth control method for the first 7 days.

Maximum Dosage Recommendations

Do not exceed the recommended doses, unless deemed necessary by your doctor.

Usual Duration of Use

The length of therapy varies depending on the need of the patient.

If You Miss a Dose

One active pill: Take one pill as soon as you remember. Then, take one more at the regular time.

Two active pills in week 1 or 2 of your cycle: Take two pills as soon as you remember and another two the next day. Use a back-up method of contraception for seven days. Contact your doctor if you miss your next period.

Two active pills in week 3 of your cycle: If you are a day 1 starter, start a new pack of pills on the same day. Also, use a back-up method of contraception for seven days. If you are a Sunday starter, take one tablet every day until the next Sunday and use a back-up method of contraception for seven days. Contact your doctor if you miss your period two months in a row.

Three active pills in any week of your cycle: If you are a day 1 starter, start a new pack of pills on the same day. Also, use a back-up method of contraception for seven days. If you are a Sunday starter, take one tablet every day until the next Sunday and use a back-up method of contraception for seven days. Contact your doctor if you miss your period two months in a row.

Storage

Keep all medications out of the reach of children

Store in a tightly closed container at room temperature in a dry, dark place. Do not store in the bathroom. Moisture can cause the drug to break down.

Special Note

For use as an emergency contraceptive -
Take 4 yellow pills within 72 hours after unprotected sex and 4 more yellow pills 12 hours later. Each dose contains 0.6 mg of levonorgestrel and 120 痢 of ethinyl estradiol.